| Sep. 3 Saturday | Rutgers Scarlet KnightsAlumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Sep. 10 Saturday | at Virginia Tech HokiesLane Stadium, Blacksburg, VA | Time TBA ETTV TBA | Buy Tickets |
| Sep. 17 Saturday | Maine Black BearsAlumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Sep. 24 Saturday | at Florida State SeminolesDoak Campbell Stadium, Tallahassee, FL | Time TBA ETTV TBA | Buy Tickets |
| Oct. 1 Saturday | Louisville CardinalsAlumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Oct. 8 Saturday | Clemson Tigers (HC)Alumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Oct. 15 Saturday | OFF | | |
| Oct. 22 Saturday | at Wake Forest Demon DeaconsTruist Field, Winston-Salem, NC | Time TBA ETTV TBA | Buy Tickets |
| Oct. 29 Saturday | at UConn HuskiesRentschler Field, East Hartford, CT | Time TBA ETTV TBA | Buy Tickets |
| Nov. 4 Friday | Duke Blue DevilsAlumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Nov. 12 Saturday | at NC State WolfpackCarter-Finley Stadium, Raleigh, NC | Time TBA ETTV TBA | Buy Tickets |
| Nov. 19 Saturday | at Notre Dame Fighting IrishNotre Dame Stadium, Notre Dame, IN | Time TBA ETTV TBA | Buy Tickets |
| Nov. 26 Saturday | Syracuse OrangeAlumni Stadium, Chestnut Hill, MA | Time TBA ETTV TBA | Buy Tickets |
| Dec. 3 Saturday | ACC ChampionshipBank of America Stadium, Charlotte, NC | Time TBA ETTV TBA | |